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Machine Learning with PLS_Toolbox/Solo

August 20, 2023

Innsbruck, Austria,

Eigenvector Research, Inc. is pleased to offer Machine Learning with PLS_Toolbox/Solo, a live, in-person short course showing how to use the advanced machine learning methods in Eigenvector software. Emphasis will be on applications in spectroscopy, Near-Infrared (NIR) in particular.

Complete information about the course can be found by following the links below.

Target Audience

Machine Learning with PLS_Toolbox/Solo is aimed at spectroscopists and other scientists who want to be able to use machine learning methods to develop their own linear and non-linear models for calibration/regression or sample classification. It is recommended that participants be familiar with Principal Components Analysis (PCA) and multivariate regression methods such as Partial Least Squares (PLS). Courses in these topics can be found on the EigenU Recorded Courses page.

Course Description

The material for this in-person course is drawn from our popular Eigenvector University Series. The course addresses linear methods briefly but will focus on machine learning methods designed to deal with non-linear data. Emphasis will be on applying these techniques to spectroscopic, especially NIR data. Methods for instrument calibration, sample classification and exploratory data analysis will be covered.

The course will focus on how to use the machine learning methods in Eigenvector’s PLS_Toolbox and Solo software. In order to take advantage of these hands-on examples participants should equip their computers with current versions of Solo or PLS_Toolbox (and MATLAB) installed. Demo copies will work just fine. Users with Eigenvector accounts can download free demos. If you don’t have an account, start by creating one.

About the Instructor

The course will be led by Eigenvector President and PLS_Toolbox creator Barry M. Wise. Dr. Wise has delivered over 200 chemometrics courses at scientific conferences, on-site for companies, on-line and at our popular Eigenvector University each year in Seattle.

Course Fee

This course is free, however you must register to attend.

How to Register, Deadlines

To register, login to your Eigenvector account, or create an account, then select the class you would like to attend under the “Purchase” tab. In order to assure a spot in the course, please register by Wednesday, August 15, 2023.


Machine Learning with PLS_Toolbox/Solo will be held at the AC Hotel Innsbruck, Salurner Strasse 15, 6020 Innsbruck, AUSTRIA. The AC Hotel is located close to the main train station and old town, and is a 14 minute walk from the Congress Center (see map below).


Schedule, Central European Time (CET)
12:30 – 13:00 Check-in
13:00 – 14:30 Instruction
14:30 – 14:45 Coffee Break (with complimentary refreshments)
14:45 – 16:00 Instruction
16:00 – 16:30 Wrap-up Discussion and Questions

Course Outlines

Machine Learning with PLS_Toolbox/Solo will cover the follow topics:

  • Classification and Regression Methods
    • Linear and Non-linear Data
    • Partial Least Squares (PLS) Regression
    • Partial Least Squares Discriminant Analysis (PLS-DA)
    • Hierarchical Modeling (HMB and HMAC)
    • Locally Weighted Regression (LWR)
    • Soft Independent Modeling of Class Analogy (SIMCA)
    • Support Vector Machine Discriminant Analysis (SVMDA)
    • Artificial Neural Networks Regression and Discriminant Analysis (ANN, ANNDA)
    • Boosted Regression Trees Discriminant Analysis (XGBoostDA)
    • Hyperspectral Image Classification (time permitting)
    • Conclusion/ Choosing Which Method
  • Data Compression for Visualization and Preprocessing
    • Brief review of Principal Components Analysis (PCA)
    • t-distributed Stochastic Neighbor Embedding (t-SNE)
    • Uniform Manifold Approximation and Projection (UMAP)
    • Conclusion/ Choosing Which Method
  • Conclusions
  • Discussion and Questions