SEARCHEVRI-thing You Need to Know About Shift Invariant Tri-linearity for Spectral Unmixing in LC/GC-MS
June 3, 2025
Eigenvector’s webinar series continues Tuesday, June 3 with “EVRI-thing You Need to Know About Shift Invariant Trilinearity for Spectral Un-mixing in LC/GC-MS.” EVRI Vice-President Neal B. Gallagher will present with help from collaborators Paul-Albert Schneide and Rasmus Bro.
High throughput pharmaceutical experiments and -omics studies rely on spectral unmixing of large multi-sample data sets generated from hyphenated chromatography measurements. To assist in this task, PLS_Toolbox 9.3 introduced ALS_SIT, a new trilinear decomposition tool for spectral un-mixing in hyphenated chromatography that accounts for peak shifting in elution profiles sample-to-sample. The ALS_SIT command line tool includes the shift invariant trilinearity (SIT) and shift invariant soft trilinearity (SIST) algorithms. In this webinar we’ll cover:
- Basic ideas behind SIT and SIST
- How to use ALS_SIT with an example data set
- Modifying options and constraints
- Future tools and applications
A question-and-answer session will follow the webinar. Don’t miss your chance to quiz Neal, Paul, Rasmus and the Eigen-Guys about how to use ALS_SIT in PLS_Toolbox!
Register for “EVRI-thing You Need to Know About Shift Invariant Trilinearity for Spectral Un-mixing in LC/GC-MS” through your existing Eigenvector account, or create one. The webinar is free, but you must register to attend. Find the webinar near the bottom of the page under the “Purchase” tab.
The webinar will be live on Tuesday, June 3 at 7:00am PDT, (that’s 16:00 CET, 10:00 EDT). Reserve your seat today and we’ll send you a WebEx meeting invitation a couple days before the event. We hope you can attend, but if you sign up and can’t make it, we’ll send you a link to view the recording the day after the webinar.