Jeremy M. Shaver, Ph.D.Chief of Technology Development,Eigenvector Research, Inc. 15835 10th Ave NE |
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Education:
Postdoctoral Research Fellow, University of Michigan, 1995-1997.
Ph.D. (Analytical Chemistry), Duke University, 1995.
B.A. (Chemistry), College of Wooster, 1991.
Experience:
June 2005 - present, Chief of Technology Development, Eigenvector
Research Inc., Manson, WA; Chemometric research, development, consultation
and software.
Feb 2001 - June 2005, Senior Scientist, Eigenvector Research Inc.,
Manson, WA; Chemometric research, development, consultation and
software.
July 1997 - Feb 2001, Applications Scientist, Kaiser Optical Systems Inc., Ann Arbor, MI; Consultation and development for new imaging, QC and on-line applications of Raman spectroscopy. Develop process and QC analysis models, software and user interfaces.
September 1995 - July 1997, Postdoctoral Research Fellow, University of Michigan, Ann Arbor, MI; Spectroscopic and chemometric research with Professor Michael Morris including vibrational image analysis, on-line detection of CE separations using Raman spectroscopy.
January 1996 - July 1997, Lecturer, University of Michigan, Ann Arbor, MI.
September 1988 - August 1995, Research & Teaching Assistant, Duke University (Durham, NC) and College of Wooster (Wooster, OH).
Research Interests:
Development and application of practical numerical analysis methods for real-life systems from chemical production to disease detection to multi-way and bio-informatics. Chemometric approaches which utilize the unique advantages of the particular analytical measurement using an understanding the analytical measurement and science of the system under study. Characterizing the limitations of the chemometrics for the particular application. Adapting powerful but simple-to-use tools for non-chemometricians.
Professional Organizations and Activies:
Sigma Xi, Scientific Research Society; American Chemical Society (Analytical Division); Society for Applied Spectroscopy; Phi Lambda Upsilon (National Honorary Chemical Society); Cascade Flyers - Vice President/Board Member (2003-present); Ann Arbor Flyers - Board Member/Webmaster (2000-2002).
Honors:
Thomas Hirschfeld Graduate Student Award, FACSS (1995); Ethyl Corporation (Lawrence E. Blanchard) Summer Fellowship (1994); Society for Applied Spectroscopy, Piedmont Section, Graduate Student Award (1994); Lubrizol Fellowship, Lubrizol Corporation Undergraduate Fellowship (1990).
Publications:
Lei, P., Jiang, G., Davis, R.C., Shaver J.M., Smentkowski, V.S., Asplund, M.C., Linford, M.R., "Laser Activation-Modification of Semiconductor Surfaces (LAMSS) of 1-Alkenes on Silicon: A ToFSIMS, Chemometrics, and AFM Analysis," submitted Appl. Surface Sci. (8/2006).
Gallagher, N.B, Shaver, J.M., Windig, W., Blake, T.A., Gassman, P.L. "Multivariate Curve Resolution Applied to Infrared Reflectance Measurements of Soil Contaminated with Organic Analyte," Appl. Spectrosc., 2006, 60(7), 713-722.
Gallagher, N.B., Shaver, J.M., Martin, E.B., Morris, J., Wise, B.M. and Windig, W. "Curve resolution for images with applications to TOF-SIMS and Raman," Chemo. and Intell. Lab. Sys., 2003, 77(1), 105-117.
Gallagher, N.B., Sheen, D.M., Shaver, J.M., Wise, B.M. and Schultz, J.F. "Estimation of Trace Vapor Concentration-Pathlength in Plumes for Remote Sensing Applications from Hyperspectral Images," SPIE Proceedings, 2003, 5093, 184-194.
Shaver, J.M. "Chemometrics for Raman Spectroscopy" in Handbook of Raman Spectroscopy, Lewis and Edwards, editors, Marcel Dekker, New York, 2001; pp 275-306.
Shaver, J. M., Christensen, K. A., Pezzuti, J. A., and Morris, M. D., "Structure of Dihydrogen Phosphate Ion Aggregates by Raman-Monitored Serial Dilution," Applied Spectroscopy, 1998, 52(2), 259-264.
Jestel, N. L., Shaver, J. M., and Morris, M. D., "Hyperspectral Raman Line Imaging of an Aluminosilicate Glass," Applied Spectroscopy, 1998, 52 (1), 64-69.
Walker III, P. A., Shaver, J. M., and Morris, M. D., "Identification of Cationic Herbicides in Deionized Water, Municipal Tap Water, and River Water by Capillary Isotachophoresis / On-Line Raman Spectroscopy," Applied Spectroscopy, 1997, 51 (9), 1394-1399.
Shaver, J. M. and McGown, L. B., "Maximum Entropy Method Analysis of Frequency-Domain Fluorescence Lifetime Data: 2. Timing, Mismatched Intensity and Reference Lifetime Errors," Analytical Chemistry, 1996, 68(4), 611-620.
Shaver, J. M. and McGown, L. B., "Maximum Entropy Method Analysis of Frequency-Domain Fluorescence Lifetime Data: 1. Effects of Frequency Range and Random Noise," Analytical Chemistry, 1996, 68(1), 9-17.
Shaver, J. M. and McGown, L. B., "Fluorescence Characterization of Complex Coal Liquid Samples using the Lifetime Synchronous Spectrum (LiSS)," Applied Spectroscopy, 1995, 49(6), 813-818.
McGown, L. B., Hemmingsen, S. L. and Shaver, J. M., "Total Lifetime Distribution Analysis for Fluorescence Fingerprinting and Characterization," Applied Spectroscopy, 1995, 49(1), 60-66.
Shaver, J. M. and McGown, L. B., "Generation of a New Spectral Format, the Lifetime Synchronous Spectrum (LiSS), using Phase-Resolved Fluorescence Spectroscopy," Applied Spectroscopy, 1994, 48(6), 755-760.
Smalley, M. B., Shaver, J. M. and McGown, L. B., "On-the-Fly Fluorescence Lifetime Detection in HPLC Using a Multiharmonic Fourier Transform Phase-Modulation Spectrofluorometer," Analytical Chemistry, 1993, 65, 3466-3472. (Selected for the 1993 Perkin-Elmer International Liquid Chromatography Technical Paper Award)
Select Presentations:
Shaver, J. M., Lei, P., Jiang, G., Asplund, M.C., Linford, M.R.,"Robust Multivariate Analysis for Problem Images," Federation of Analytical Chemistry and Spectroscopy Societies, Lake Buena Vista, FL, September 24-28, 2006.
Bryan, S. A., Levitskaia, T.G., Sinkov, S.I., Schlahta, S.N., Shaver, J.M., "Raman based process monitor for continuous real-time analysis of high level radioactive waste components," Meeting of the American Chemical Society, San Francisco, CA, September 10-14, 2006.
Shaver, J. M., Wise, B. M., Koch, R. S., "Expanding Chemometric Model Sophistication for Improved Performance in Industrial Applications," Eastern Analytical Simposium, Somerset, NJ, November 13-16, 2005.
Shaver, J. M., "Using pre-whitening techniques for process model stabilization," Federation of Analytical Chemistry and Spectroscopy Societies, Quebec City, Quebec, Canada, October 9-13, 2005.
Shaver, J. M., Gallagher, N.B., Wise, B.M., "Using MATLAB and PLS_Toolbox for Online Process Monitoring," International Forum on Process Analytical Chemistry, Arlington, VA, January 10-13, 2005.
Shaver, J. M., Wise, B.M. "Chemometric Techniques for Two-way, Three-way and Higher-order Image Data," AVS 51st International Symposium, Anaheim, CA, November 14-19, 2004.
Wise, B. M. and Shaver, J. M. "Detection of Cervical Cancer from Evoked Tissue Fluorescence Images using 2- and 3-Way Methods," Eastern Analytical Symposium, New Jersey, November, 14-19, 2004.
Shaver, J. M., Bryan, S.A, Levitskaia, T.G., and Sinkov, S.I. "Raman Analysis of Concentrated Salt Solutions Using Robust Modeling and Data Fusion," Federation of Analytical Chemistry and Spectroscopy Societies, Portland, OR, October 3-7, 2004.
Wise, B. M. and Shaver, J. M. "Classification of Cervical Tissue with Evoked Tissue Fluorescence Images using 2- and 3-Way Methods," Chemometrics in Analytical Chemistry, Lisbon, Portugal, September 20-23, 2004.
Shaver, J.M., Gallagher, N.B and Bro, R.B, "Local Functional Constraints in Multivariate Curve Resolution," Federation of Analytical Chemistry and Spectroscopy Societies, Portland, OR, October 19-23, 2003.
Shaver, J.M. "Finding Specificity in Multivariate Curve Resolution," Federation of Analytical Chemistry and Spectroscopy Societies, Portland, OR, October 19-23, 2003.
Shaver, J.M., Gallagher, N.B. and Martin, E.B. "Multivariate Curve Resolution of Hyperspectral Images: Initialization and Functional Constraints," 8th Scandinavian Symposium on Chemometrics, Aland, Finland, June 14-18, 2003.
Shaver, J. M., Gallagher, N.B., Wise, B.M., Martin, E.B. "Multivariate Curve Resolution of Hyperspectral Images: Ambiguities and Low-Signal Components," Spectrum-Imaging and Hyperspectral Data Analysis Workshop - Microbeam Analysis Society, Gaithersburg, MD, April 28-May 1, 2003.
Gallagher, N.B., Shaver J.M., Martin, E.B., Thennadil, S.N. "Hyperspectral Imaging for Process Monitoring and Process Analytical Chemistry" International Forum on Process Analytical Chemistry, Phoenix, AZ, January 21-24, 2003.
Shaver, J. M., Wright, S. "Automatic Declutter Approaches using GLS with Discrete or Continuous Independent Variables," Chemometrics in Analytical Chemistry, Seattle WA, Sept. 22-26, 2002.
Shaver, J. M., Wise, B.M., Gallagher, N.B. "Thinking Outside the POX - Alternatives for Stable Model Design," Annual Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies, Detroit, MI, October 8-12, 2001.
Shaver, J. M. "Correction Of Instrumental Artifacts In Raman Spectroscopy And Its Effect On Chemometric Models," Annual Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies, Detroit, MI, October 8-12, 2001.
Shaver, J. M. "Raman Calibration and Calibration Transfer using Full-Ratio PCR and Piecewise Gaussian Blurring," Gordon Research Conference on Statistics in Chemistry and Chemical Engineering, Williams College, Williamstown, MA, July 22-27, 2001.
Shaver, J. M. "Spectral Analysis Techniques - Getting Process Raman to WORK," International Forum on Process Analytical Chemistry, Amelia Island, FL, January 21-24, 2001.
Shaver, J. M. "A Semi-Quantitative/Quantitative Platform for Reaction Monitoring and On-Line Raman Analyses", Annual Meeting of the Center for Process Analytical Chemistry, Seattle, WA, November 6, 2000.
Shaver, J. M. "Analytical Chemistry for Control of Chemical Reactors in Industry", University of Michigan, Ann Arbor, MI, October 5, 2000.
Shaver, J. M. "Using the Raman Advantage in Real-Time Quantitative Reaction Monitoring", Annual Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies, Nashville, TN, September 25-29, 2000.
Lewis, I. R., Shaver, J. M., Samford M.L. "Advances in Fiber-Coupled Raman Microprobes and Chemical Mapping", International Union of Microbeam Analysis Societies, Kona, HI, July 10-14, 2000.
Shaver, J. M. "Modeling and Instrumentation for Accurate On-Line Raman Measurements", International Forum on Process Analytical Chemistry, Las Vegas, NV, January 24-26, 2000.
Shaver, J. M. "Stabilizing Multi-Component Process Models-New Approaches Using Relative Intensity", Federation of Analytical Chemistry and Spectroscopy Societies, Vancouver, BC, October 25-29, 1999.
Shaver, J. M. "Simple and Robust Models for Process Raman Spectral Analysis", The Pittsburgh Conference, Orlando, FL, March 7-12, 1999.
Shaver, J. M. and Pelletier, M. J. "Breaking Convention for Process-Suitable Raman Models", Society for Applied Spectroscopy, Chicago section, Naperville, IL, February, 17, 1999.
Shaver, J. M. "The Pursuit of Stable Process-Raman Models for an Uncertain World", Invited talk, Anachem / Society for Applied Spectroscopy, Detroit, MI, November, 1, 1998.
Shaver, J. M. "Analytical Laser Spectroscopy for Industrial Process Monitoring and Quality Control", Invited talk, Ohio Weslean University, Deleware, OH, October, 1, 1998.
Shaver, J. M. and Leugers, A. "On-Line Raman for Polyethylene Process Monitoring and Control", Gulf Coast Conference, Galveston, TX, September, 15-17, 1998.
Shaver, J. M. and Pelletier, M. J. "Raman Analyzers for Polymer Production and Processing", Workshop, Gulf Coast Conference, Galveston, TX, September, 15-17, 1998.
Shaver, J. M. "Modern Process Raman Applications - From Benchtop to Rooftop", Society for Applied Spectroscopy, Chicago section, Naperville, IL, February, 25, 1998.
Shaver, J. M. "Raman Spectroscopy", Workshop, Eastern Analytical Symposium, New Jersey, November, 1997.
Shaver, J. M., Jestel, N. L., and Morris, M. D., "Multivariate Analysis of Hyperspectral Raman Data of Complex Samples," The Pittsburgh Conference, Atlanta, GA, 3/16-21/1997.
Morris, M. D., Walker III, P .A., and Shaver, J. M., "Raman Spectroscopy/Capillary Electrophoresis - Ultrasensitivty via On-line Preconcentration," The Pittsburgh Conference, Atlanta, GA, 3/16-21/1997.
Pezzuti, J. A., Shaver, J. M., and Morris, M. D., "Raman Microscopy of Crystallizing Amino Acids and Carboxyllic Acids," The Pittsburgh Conference, Atlanta, GA, 3/16-21/1997.
Jestel, N. L., Shaver, J. M., and Morris, M. D., "Raman Microspectroscopy and Hyperspectral Raman Imaging of Silicate Glasses," The Pittsburgh Conference, Atlanta, GA, 3/16-21/1997.
Shaver, J. M., Christensen, K. A. and Morris, M. D., "Multivariate Techniques for Raman Image Enhancement," 23nd Annual Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies, Kansas City, MO, 9/29-10/4/96.
Morris, M. D., Shaver, J. M., Christensen, K. A. and Bradley, N. L., "Getting the Most Out of the Least: Data Transformation in Raman Microspectroscopy and Imaging," 23nd Annual Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies, Kansas City, MO, 9/29-10/4/96.
Christensen, K. A., Shaver, J. M. and Morris, M. D., "Micro-Raman Studies of Crystalline Phosphates," 23nd Annual Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies, Kansas City, MO, 9/29-10/4/96.
Shaver, J. M., Bonney, J. L. and Morris, M. D., "Modern Raman Spectroscopy for Undergraduate Analytical Laboratories," 212th American Chemical Society National Meeting, Orlando, FL, 8/25-29/96.
Shaver, J. M., Walker III, P. W. and Morris, M. D., "Statistically-Based Correlation Analyses in Raman-Detected Capillary Electrophoretic Separations," 15th International Conference On Raman Spectroscopy, Pittsburgh, PA, 8/11-15/96.
Bradley, N. L., Shaver, J. M. and Morris, M. D., "Examination of Glassy Materials by Raman Microspectroscopy and Imaging," 15th International Conference On Raman Spectroscopy, Pittsburgh, PA, 8/11-15/96.
Walker III, P. W., Shaver, J. M. and Morris, M. D., "Detection of Isotachophoretically Separated Quanternary Cationic Herbicides," 15th International Conference On Raman Spectroscopy, Pittsburgh, PA, 8/11-15/96.
Christensen, K. A., Shaver, J. M. and Morris, M. D., "A Raman Spectroscopic and Imaging Study of Aqueous KDP and NaDP Freezing Phenomena in a Buffer System," 15th International Conference On Raman Spectroscopy, Pittsburgh, PA, 8/11-15/96.
Shaver, J. M., Lee, S. S. and McGown, L. B., "Elucidation of Molecular Probe Distributions in Reverse Micelles by Total Lifetime Distribution Analysis (TLDA)," Featured Presentation, 22nd Annual Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies, Cincinnati, OH, 10/15-20/95.
Shaver, J. M., Hemmingsen, S. L., Joseph, M. J. and McGown, L. B., "Rethinking Phase and Modulation Analysis: Novel Data Analysis Techniques and Considerations for the New Generation of Frequency-Domain Fluorescence Lifetime Instrumentation," The Pittsburgh Conference, New Orleans, LA, 3/5-10/95.
Shaver, J. M. and McGown, L. B., "Complex Sample Analysis Using Novel Phase-Resolved Fluorescence Spectroscopic Techniques," Invited Speaker, The Society for Applied Spectroscopy Piedmont Section Annual Meeting, Athens, GA, 3/31/1994.
Shaver, J. M. and McGown, L. B., "Characterization of Coal Liquid Samples Using Novel Phase-Resolved Fluorescence Spectroscopic Techniques," The Pittsburgh Conference, Chicago, IL, 2/27-3/4/1994.
Shaver, J. M. and McGown, L. B., "Novel Spectral and Lifetime Resolved Fluorescence Techniques," The Society of Photo-optical Instrumentation Engineers' International Symposium on Biomedical Optics, Los Angles, CA, 1/22-28/1994.
Shaver, J. M. and McGown, L. B., "Characterization of Residuum-Derived Vacuum Gas Oil Samples Using Phase-Resolved Fluorescence Spectroscopy," The Pittsburgh Conference, Atlanta, GA, 3/7-12/1993.
Shaver, J. M. and McGown, L. B., "Improved Characterization of Complex Coal Liquid Samples Using Phase-Resolved Fluorescence Spectroscopy," The 19th Annual Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies, Philadelphia, PA, 9/20-25/1992.
